SR-121463A CAS;
价格:12000元/公斤 含量:99% 包装:25公斤
CAS;
分子式：C17H22ClNO3
分子量：323.8228
化学名称 N-tert-Butyl-4-[5'-ethoxy-4-[2-(4-morpholinyl)ethoxy]-2'-oxospiro[cyclohexane-1,3'-indolin]-
1'-ylsulfonyl]-3-methoxybenzamide fumarate
The reduction of diethyl 3-(methoxymethoxy)glutarate (I) with LiAlH4 in THF gives 3-(methoxymethoxy)pentane-
1,5-diol (II), which is treated with Ts-OH and TEA in THF to yield the disulfonate (III). The condensation of
(III) with 5-ethoxyindolin-2-one (IV) by means of tBu-OK in THF affords the spiro compound (V), which is
deprotected with HCl in methanol to afford the spiranic alcohol (VI). The oxidation of (VI) with pyridinium
chlorochromate (PCC) over Al2O3 provides the spiranic cyclohexanone (VII), which is treated with 2-
chloroethanol (VIII) and Ms-OH in toluene to give the ketal (IX). The reaction of (IX) with zinc borohydride
and trimethylsilyl chloride in ethyl ether/dichloromethane yields the 2-chloroethoxy derivative (X), which is
condensed with 4-(N-tert-butylcarbamoyl)-2-methoxybenzenesulfonyl chloride (XI) by means of tBu-OK in THF to
afford the adduct (XII). Finally, the target compound is obtained by condensation of (XII) with morpholine
(XIII) by means of NaI in DMF, followed by treatment with fumaric acid.
尼朦尔可素 包装:50克/瓶 价格:1300元/瓶 红色粉末
还阳碱 CAS号： 8600元/公斤
金阳碱 CAS号：54060-92-3 4600元/公斤
新阳碱 36-12-87 4600元/公斤
虾青素 CAS号：472-61-7 8600元/公斤
CAS号：
MAB-CHMINAC
5FADB
FUB-AMB
CAS号：70434-92-3 CP 47,497 CAS号：952016-47-6 8492312-32-2
CAS号：84485-00-7 12 125494-59-9 CAS： CAS：
原料与成品三包服务: CAS:90717-16-1;299-42-3;6740-85-81867-66-9;51062-14-7; CAS:2114-00-3;2011-67-8;5650-44-
2;103-79-7 CAS:4468-48-8;103-79-7;51-57-0;6740-88-1;936-59-4;60124-79-0;125-79-1 CAS:76-99-3;118-92-3;2538-
50-3;340-56-7;82-58-6;51753-57-2;58-08-2
